Analysis of bacterial multidrug-resistant microorganism infections in intensive care patients

Maria de los Angeles  Flores Garcia; Sandra Arcieri Sandra Arcieri

doi:10.59471/ijhsc2023153

Authors

Maria de los Angeles Flores Garcia Facultad de Medicina y Ciencias de la Salud, Universidad Abierta Interamericana. Argentina Author https://orcid.org/0000-0003-1782-392X
Sandra Arcieri Facultad de Medicina y Ciencias de la Salud, Universidad Abierta Interamericana. Argentina Author https://orcid.org/0000-0003-2310-0007

DOI:

https://doi.org/10.59471/ijhsc2023153

Keywords:

Multidrug-Resistant Organisms, Intensive Care Units, Infection, Infection Control, Incidence

Abstract

Introduction: in-hospital infections cause significant morbidity and mortality. They affect approximately 45 % to 51 % of patients treated in intensive care. The intensive care unit (ICU) is a high-risk facility for the emergence and spread of multidrug-resistant organisms. The World Health Organization (WHO) classified pathogens of priority concern from level 1 to level 3.

Method: the study design was a retrospective observational cohort study. Data were collected from seventy clinical histories of the Hospital General de Agudos Donación Francisco Santojanni, located in the city of Buenos Aires, CABA, in the intensive care unit, during a period of 6 months.

Results: a review of 70 medical records was made, of which 14 records presented infections by multiresistant microorganisms, representing 20 % of them.

Conclusions: in-hospital infections will always be present, the important thing is to minimize them and assist them early, ideally to avoid them, so care must be taken in the organization of procedures with all aseptic measures

References

Mesquita Paes AR, Teixeira Câmara J, Silva dos Santos DA, Cardoso Portela NL. Epidemiological study of cross infection in Intensive Care Unit/Estudo epidemiológico de infecção hospitalar em Unidade de Terapia Intensiva/Estudio epidemiológico de la infección hospitalaria en Unidad de Cuidados Intensivos. Rev Enferm UFPI. 1 de diciembre de 2014;3(4):10.

Londoño Restrepo J, Macias Ospina IC, Ochoa Jaramillo FL. Factores de riesgo asociados a infecciones por bacterias multirresistentes derivadas de la atención en salud en una institución hospitalaria de la ciudad de Medellín 2011-2014. Infectio. abril de 2016;20(2):77-83.

Litwin A, Fedorowicz O, Duszynska W. Characteristics of Microbial Factors of Healthcare-Associated Infections Including Multidrug-Resistant Pathogens and Antibiotic Consumption at the University Intensive Care Unit in Poland in the Years 2011–2018. Int J Environ Res Public Health. 23 de septiembre de 2020;17(19):6943.

Kernéis S, Lucet JC. Controlling the Diffusion of Multidrug-Resistant Organisms in Intensive Care Units. Semin Respir Crit Care Med. agosto de 2019;40(04):558-68.

Ortiz López C. Diseño, síntesis, caracterización y evaluación in vitro de la actividad de los péptidos resistentes a antibióticos. Rev Acad Colomb Cienc antimicrobianos contra bacterias patógenas Exactas Físicas Nat. 15 de noviembre de 2019;43(169):614-27.

Pujol M, Limón E. Epidemiología general de las infecciones nosocomiales. Sistemas y programas de vigilancia. Enfermedades Infecc Microbiol Clínica. febrero de 2013;31(2):108-13.

Dominedò C, Ceccato A, Niederman M, Cillóniz C, Gabarrús A, Martin-Loeches I, et al. Predictive Performance of Risk Factors for Multidrug-Resistant Pathogens in Nosocomial Pneumonia. Ann Am Thorac Soc. mayo de 2021;18(5):807-14.

Cilloniz C, Martin-Loeches I, Garcia-Vidal C, San Jose A, Torres A. Microbial Etiology of Pneumonia: Epidemiology, Diagnosis and Resistance Patterns. Int J Mol Sci. 16 de diciembre de 2016;17(12):2120.

Chang Y, Jeon K, Lee SM, Cho YJ, Kim YS, Chong YP, et al. The Distribution of Multidrug-resistant Microorganisms and Treatment Status of Hospitalacquired Pneumonia/Ventilator-associated Pneumonia in Adult Intensive Care Units: a Prospective Cohort Observational Study. J Korean Med Sci. 2021;36(41):e251.

Busani S, Serafini G, Mantovani E, Venturelli C, Giannella M, Viale P, et al. Mortality in Patients With Septic Shock by Multidrug Resistant Bacteria: Risk Factors and Impact of Sepsis Treatments. J Intensive Care Med. enero de 2019;34(1):48-54.