Comparative study between physiological healing vs. the use of platelet-rich fibrin at the time of bone and gingival tissue healing in lower third molar surgeries. Bibliographic Review
DOI:
https://doi.org/10.59471/ijhsc2024122Keywords:
Healing, platelet-rich fibrin, third molars, bone tissue, gingival tissueAbstract
Introduction: The extraction of retained third molars can present surgical complications, causing various alterations to the patient, such as pain after the intervention, inflammation during the next 24 to 72 hours, jaw pain, among others.
Objective: To compare the effectiveness of physiological healing vs. the use of platelet-rich fibrin at the time of bone and gingival tissue healing in lower third molar surgeries by means of a bibliographic review and thereby identify the properties and factors that promote healing. cicatrization.
Materials and methods: Qualitative and descriptive bibliographic review, based on the PRISMA (2020) method, inclusion and exclusion criteria were used, in addition to search strings created using MeSH terms and Boolean operators to search the databases, PubMed, ScienceDirect, and Scielo.
Results: A total of 12 scientific articles with valid information for the investigation were obtained. It was determined that platelet-rich fibrin is better than physiological healing for bone and gingival tissue healing in lower third mandibular surgeries.
Conclusion: It is concluded that the application of Platelet Rich Fibrin (PRF) promotes the healing process of the tissues and reduces discomfort such as pain, inflammation and bleeding after mandibular third molar surgery, although advanced Platelet Rich Fibrin variants (A-PRF) and leukocyte- and platelet-rich fibrin (L-PRF) are more efficient than simple PRF
References
Guzmán G, Paltas M, Benenaula J, Núñez K, Simbaña D. Cicatrización de tejido óseo y gingival en cirugías de terceros morales inferiores. Estudio comparativo entre el uso de fibrina rica en plaquetas versus cicatrización fisiológica. Rev Odontológica Mex [Internet]. 2017;21(2):114–20. Available from: https://www.scielo.org.mx/pdf/rom/v21n2/1870-199X-rom-21-02-00114.pdf
Castagna V, Pardo A, Lanaro L, Signoriello A, Albanese M. Periodontal Healing after Lower Third Molars Extraction: A Clinical Evaluation of Different Flap Designs. Healthc (Basel, Switzerland) [Internet]. 2022 Aug;10(8):1–13. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408120/
Zhang Y, Chen X, Zhou Z, Hao Y, Li H, Cheng Y, et al. Effects of impacted lower third molar extraction on periodontal tissue of the adjacent second molar. Ther Clin Risk Manag [Internet]. 2021;17(1):235–47. Available from: https://www.dovepress.com/getfile.php?fileID=67863
Salgado Á, Salgado Á, Arriba L. Nuevas tendencias en regeneración tisular: fibrina rica en plaquetas y leucocitos. Rev Esp Cir Oral y Maxilofac [Internet]. 2017;39(2):91–8. Available from: https://scielo.isciii.es/pdf/maxi/v39n2/1130-0558-maxi-39-02-00091.pdf
Hanif M, Sheikh MA. Efficacy of platelet rich plasma (PRP) on mouth opening and pain after surgical extraction of mandibular third molars. J Oral Med Oral Surg [Internet]. 2021;27(1):3–9. Available from: https://www.jomos.org/articles/mbcb/pdf/2021/01/mbcb200021.pdf
Travezán M, Aguirre A, Arbildo H. Effect of the Platelet-Rich Fibrin on the Healing of the Soft Tissues of Sockets after Atraumatic Exodontics. A Single-Blind Cross-Randomized Controlled Clinical Trial. Int J Odontostomat [Internet]. 2021;15(1):240–7. Available from: https://www.scielo.cl/pdf/ijodontos/v15n1/0718-381X-ijodontos-15-01-240.pdf
Alencastro S, Ordóñez C. Complications in the extraction of impacted , and retained third molars . Literature Review . Rev Odontol Vital [Internet]. 2023;1(38):26–33. Available from: https://www.scielo.sa.cr/pdf/odov/n38/en_1659-0775-odov-38-17.pdf
López E, Pascual A. Fibrina rica en plaquetas en la cicatrización de los tejidos periodontales. Odontol Sanmarquina [Internet]. 2020;23(1):43–50. Available from: https://docs.bvsalud.org/biblioref/2020/03/1053510/17506-texto-del-articulo-60950-1-10-20200221.pdf
Esra E. The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites. Cumhur Dent J [Internet]. 2018;21(4):304–10. Available from: http://cdj.cumhuriyet.edu.tr/en/download/article-file/617841
Makki A, Alsulami A, Almatrafi A, Sindi M, Sembawa S. The Effectiveness of Advanced Platelet-Rich Fibrin in comparison with Leukocyte-Platelet-Rich Fibrin on Outcome after Dentoalveolar Surgery. Int J Dent [Internet]. 2021;21(1):1–9. Available from: https://downloads.hindawi.com/journals/ijd/2021/6686857.pdf
Sharma A, Ingole S, Deshpande M, Ranadive P, Sharma S, Kazi N, et al. Influence of platelet-rich fibrin on wound healing and bone regeneration after tooth extraction: A clinical and radiographic study. J oral Biol craniofacial Res [Internet]. 2020;10(4):385–90. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393389/
Cruz C, Castro Y. Resultados de los concentrados plaquetarios en la regeneración ósea guiada. Rev Cuba Investig Biomed [Internet]. 2020;39(2):1–20. Available from: http://scielo.sld.cu/pdf/ibi/v39n2/1561-3011-ibi-39-02-e515.pdf
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. Declaración PRISMA 2020: una guía actualizada para la publicación de revisiones sistemáticas. Rev Española Cardiol. 2021;74(9):790–9.
Afat I, Akdoğan E, Gönül O. Effects of leukocyte- and platelet-rich fibrin alone and combined with hyaluronic acid on early soft tissue healing after surgical extraction of impacted mandibular third molars: A prospective clinical study. J Craniomaxillofac Surg [Internet]. 2019 Feb;47(2):280–6. Available from: https://pubmed.ncbi.nlm.nih.gov/30579747/
Zahid T, Nadershah M. Effect of Advanced Platelet-rich Fibrin on Wound Healing after Third Molar Extraction: A Split-mouth Randomized Double-blind Study. J Contemp Dent Pract [Internet]. 2019 Oct;20(10):1164–70. Available from: https://pubmed.ncbi.nlm.nih.gov/31883251/
Shruthi T, Shetty A, Akash K, Ahmed F, Shetty N, Singarapu R. Evaluation of effects of platelet-rich fibrin on treatment outcomes after impacted mandibular third molar surgery: A randomized controlled clinical study. Natl J Maxillofac Surg [Internet]. 2022 Aug;13(1):46–51. Available from: https://pubmed.ncbi.nlm.nih.gov/36393932/
Ritto F, Pimentel T, Canellas J, Junger B, Cruz M, Medeiros P. Randomized double-blind clinical trial evaluation of bone healing after third molar surgery with the use of leukocyte- and platelet-rich fibrin. Int J Oral Maxillofac Surg [Internet]. 2019 Aug;48(8):1088–93. Available from: https://pubmed.ncbi.nlm.nih.gov/30910410/
Caymaz M, Uyanik L. Comparison of the effect of advanced platelet-rich fibrin and leukocyte- and platelet-rich fibrin on outcomes after removal of impacted mandibular third molar: A randomized split-mouth study. Niger J Clin Pract [Internet]. 2019 Apr;22(4):546–52. Available from: https://pubmed.ncbi.nlm.nih.gov/30975961/
Torul D, Omezli M, Kahveci K. Evaluation of the effects of concentrated growth factors or advanced platelet rich-fibrin on postoperative pain, edema, and trismus following lower third molar removal: A randomized controlled clinical trial. J Stomatol oral Maxillofac Surg [Internet]. 2020 Dec;121(6):646–51. Available from: https://pubmed.ncbi.nlm.nih.gov/32068167/
Njokanma A, Fatusi O, Ogundipe O, Arije O, Akomolafe A, Kuye O. Does platelet-rich fibrin increase bone regeneration in mandibular third molar extraction sockets? J Korean Assoc Oral Maxillofac Surg [Internet]. 2022 Dec;48(6):371–81. Available from: https://pubmed.ncbi.nlm.nih.gov/36579909/
Alam S, Khare G, Arun Kumar K. A Comparative Study of Platelet-Rich Fibrin and Platelet-Rich Fibrin with Hydroxyapatite to Promote Healing of Impacted Mandibular Third Molar Socket. J Maxillofac Oral Surg [Internet]. 2022 Jun;21(2):608–15. Available from: https://pubmed.ncbi.nlm.nih.gov/35712405/
Riaz R, Radhakrishnan M, Perumal J. Comparative Study of the Efficacy of Advanced Platelet-rich Fibrin and Standard Platelet-rich Fibrin in Mandibular Third Molar Surgery. J Pharm Bioallied Sci [Internet]. 2022 Jul;14(1):781–7. Available from: https://pubmed.ncbi.nlm.nih.gov/36110692/
Yüce E, Kömerik N. Potential effects of advanced platelet rich fibrin as a wound-healing accelerator in the management of alveolar osteitis: A randomized clinical trial. Niger J Clin Pract [Internet]. 2019 Sep;22(9):1189–95. Available from: https://pubmed.ncbi.nlm.nih.gov/31489852/
Sybila D, Sawai M, Faisal M, Singh S, Jain V. Platelet-Rich Fibrin for Hard- and Soft-Tissue Healing in Mandibular Third Molar Extraction Socket. Ann Maxillofac Surg [Internet]. 2020;10(1):102–7. Available from: https://pubmed.ncbi.nlm.nih.gov/32855924/
Published
Issue
Section
License
Copyright (c) 2024 Mónica Alexandra Acosta Vargas , Ronald Medardo Gómez Coba, Jhoseline Melissa Pérez Villacrés, Mónica Sofía Pallo Sarabia (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.
How to Cite
